A-Alpha Bio is an early-stage and rapidly-growing drug discovery company headquartered in Seattle, WA. We are enabling the next generation of high-impact therapeutics by combining high-throughput synthetic biology with state-of-the-art machine learning. We partner with leading pharma and biotech companies to enable the discovery of antibodies, molecular glues, and other protein interaction-related drugs. In parallel, we use our AlphaSeq technology internally to build a Biologics Pipeline for clinical development and/or asset licensing opportunities.
This role is not open to remote applicants and would require relocation to Seattle, WA.
Starting Salary Range: $63,000 - $70,000 per year
Exemption Status: Non-Exempt
Location Expectations: Onsite
A-Alpha Bio is seeking a Research Associate I (Technical Operations) to execute workflows supporting our AlphaSeq platform for drug discovery and optimization. In this role, you will execute specific AlphaSeq elements, including the preparation of yeast strains and yeast libraries, as well as the execution of yeast matings and defined workflow requests following established protocols (or with general guidance for non-standard operations). This role also maintains an adequate supply of media, competent yeast, and other intermediate reagents used in the execution of the AlphaSeq assay and includes the execution of multi-parametric flow cytometry to confirm protein expression in yeast libraries and strains. Responsibilities may also include isolation and amplification of yeast gDNA to support Next-Generation Sequencing and assembly of standard parts for DNA library construction.
We offer competitive compensation, including benefits and equity in a fast-growing start-up. Applicants must have legal authorization to work in the United States.
About A-Alpha Bio
A-Alpha Bio is an early-stage biotechnology company combining synthetic biology and machine learning to dramatically improve the discovery of high-impact therapeutics. We believe that abundant high-quality data is critical for understanding biology and curing disease – and synthetic biology is our catalyst. Our proprietary AlphaSeq platform uses genetically engineered cells to quantitatively measure millions of protein interactions – from which we generate high-resolution models of biology.
In 2018, we spun out of the University of Washington’s Institute for Protein Design and Center for Synthetic Biology – both fantastic communities of brilliant and highly entrepreneurial scientists. Since the company’s inception, we have focused on partnering with pharmaceutical companies to discover and optimize drugs for therapeutic areas ranging from infectious disease to cancer. We are growing rapidly, and new members of the team should expect a fast-paced and highly dynamic work environment. We are building a diverse, meritocratic, and supportive team that shares our values of speaking the truth, shooting for the moon, taking the reins, playing for the team, and improving the world.
A-Alpha Bio is headquartered in a brand-new combined office/lab space in downtown Seattle's Belltown neighborhood. While the startup lifestyle occasionally requires grueling hours, we strongly value the need for a work-life balance and time out of the lab/office. We are fortunate to be situated in a region that is renowned for its premier outdoor activities, including hiking, biking, climbing, skiing, kayaking, and sailing. At A-Alpha, you’ll find many who love the outdoors, but also gamers, amateur chefs, explorers, sports fans, bakers, crafters, photographers, brewers, jetsetters, animal lovers, and artists. Whatever your passions, you belong at A-Alpha Bio.