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This role is not open to remote applicants and would require relocation to Seattle, WA.

Starting Salary Range: $140,000 - $159,000 annually

Exemption Status: Exempt

Location Expectations: Onsite

A-Alpha Bio is seeking an experienced cellular immunologist to join our Immunobiology team working towards the advancement of our therapeutic programs. This person will be responsible for executing and managing experiments to characterize the pharmacodynamic activity of internal drug candidates, and should be able to demonstrate expertise with in vitro cellular functional assays and ex vivo sample analysis.

Key Responsibilities

• Develop new in vitro functional assays to evaluate potency and selectivity of biologic candidates.
• Establish workflows for the generation and analysis of RNAseq datasets to enable high-dimensional and high-throughput immune phenotyping in various cell types, organs, and tissues.
• Present experimental findings at group meetings to support program-level, data-driven decisions.
• Nominate and lead therapeutic asset programs as needed.
• Actively participate in cross-functional teams and provide immunobiology strategic guidance to the greater department.
• Assist with the preparation of scientific publications and technical documents, including external presentations, manuscripts, and regulatory filings.
• Mentor and train junior scientific team members, including potentially serving as direct manager.
• Apply scientific rigor to all aspects of the job, including experimental design, execution, analysis, and interpretation.
• Maintain a strong and creative team culture with a clear understanding of project timelines, deliverables, and priorities.
• Perform other duties as assigned.

Qualifications & Experience

Required

• PhD in a relevant field and 4+ years of relevant experience; Bachelor's degree in a relevant field and 12+ years of relevant laboratory experience, including 6+ years of specialized immunobiology experience in the biotechnology industry; or an equivalent combination of education and experience.
• Formal immunology background.
• Expertise in flow cytometry, AlphaLISA, ELISA, RNAseq, and other common functional assay formats.
• Expertise in human and mouse primary cell immune subset isolation and stimulations.
• Expertise in immunotherapy drug development and immunoassay optimization.
• Strong written and oral communication skills, with the ability to interact with groups in a dynamic startup team environment.
• Excellent interpersonal skills to foster a fun, open, and collaborative team environment.

Preferred

• Experience with in vivo disease modeling.
• Experience leading cross-functional program teams.
• Expertise in molecular biology, next-generation sequencing, and/or yeast biology.
• Proficiency in biolayer interferometry assays utilizing Octet/Gator BLI systems.
• Experience mentoring and developing the careers of direct reports.