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Bioinformatics Scientist



New York, NY, USA
Posted on Monday, November 4, 2019

Bioinformatics Scientist

New York, NY


We are looking for a highly creative and innovation-driven Bioinformatics Scientist to lead software R&D at Envisagenics. Envisagenics is a highly multidisciplinary group combining software engineers, UX designers, computational biologists and pharma partners. We look for team players eager to integrate a founding team whose vision is finding better drug targets to cure yet incurable diseases using biological Big Data. We are looking for experts in machine learning, Genomics, RNA-seq and/or biological data interpretation. Candidates will be responsible for developing analytical approaches, hypothesis-driven data interrogation and application of predictive models for the identification of therapeutic targets to make fundamental contributions to understanding disease biology and therapy.


  • Development of algorithms and machine learning applications for
  • RNA-seq analysis, biological interpretation and disease gene prioritization.
  • Conduct objective evaluation and comparison of bioinformatics tools.
  • Work collaboratively with other team members to implement QC assessment and standardized analysis protocols for each of the projects as appropriate.
  • Apply statistical data analysis to support assay development experiments and guide experimental approaches.
  • Implement new analysis methods in the pipelines based on R&D prototypes.
  • Automate reporting of pipeline results for R&D experiments.
  • Writing of scientific manuscripts and patent applications.


  • PhD in Computational Biology.
  • Strong programming with R/Bioconductor and python.
  • Experience with C++, perl, or other scripting languages.
  • Experience with building / supporting / using bioinformatics pipelines.
  • Experience with statistical and mathematical modeling with genomic data.
  • Experience with machine learning, Bayesian statistics, clustering/classification, multivariate analysis.
  • Experience with genomic analysis of sequencing data – CLIP-Seq, RNA-Seq.
  • Experience with network analysis and visualization.
  • Ability to work in an Agile environment.
  • Must be independent and strategically minded, team-oriented.
  • Must have proficient written, communication and presentation skills.

Preferred Skills

  • Experience with cloud services such as Google Cloud, Microsoft Azure or Amazon AWS.
  • Experience with SQL and MySQL.

About Us

Envisagenics is a bioinformatics startup developing cloud-based solutions to leverage biomedical big data and accelerate R&D therapeutics through machine learning. Envisagenics is a spin-off from Cold Spring Harbor Laboratory, a biomedical research institute ranked #1 worldwide for scientific impact in the field of genetics. Envisagenics’ core technology, SpliceCore was developed by our CTO while at Cold Spring Harbor Laboratory in Dr. Adrian Krainer’s Laboratory, a leader in the RNA splicing field who was also a developer of Spinraza (Nusinersen), the first FDA-approved drug to treat children with Spinal Muscular Atrophy. The mission of Envisagenics is to materially advance the world’s ability to cure diseases, discovering new and more efficient drug targets through the analysis and integration of genomic data alongside our pharma partners.