Invest in your career with a Madrona-funded company.

The hiring pay range for this position is based on skills, education and experience relevant to the role; title may be assessed one level lower or higher, accordingly. Other components of total compensation include a competitive options grant at the time of hire (with potential for additional grants).

Benefits include medical, vision, and dental insurance, group and supplemental life insurance, 401k retirement plan, responsible (unlimited) paid time off, parental leave, and more.

At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.

We are hiring for a Director, Operations to join our growing team. This role is a critical leadership position responsible for ensuring Nautilus's Instrument and Flow Cell Operations meet commercialization timelines and compliance standards. As a leader in this position, you will translate the company's strategy into clear operational roadmaps and act as a trusted advisor to the executive team. You will have the opportunity to build and manage high-performing teams and contribute to a mission-driven culture as you help us bring our platform to the world.

Responsibilities

• Develop and execute operational strategies aligned with company objectives.

• Manage timelines and deliverables for product development and commercialization.

• Oversee the production of flowcells and instruments.

• Manage the supply chain and logistics, including sourcing, inventory, and distribution of materials and products. You'll also be responsible for architecting complex supply chains with multiple partners.

• Ensure operations comply with FDA, GMP, ISO, and other relevant regulatory standards.

• Control operational budgets and resource allocation.

• Collaborate with cross-functional teams, including R&D, QA/QC, and commercial teams, to drive results.

• Implement and optimize systems for quality assurance and control.

• Lead process improvement initiatives to enhance efficiency and scalability.

• Build and manage teams across manufacturing, supply chain, and logistics, fostering a culture of accountability and innovation.

• Report on operational performance metrics to senior management and adjust tactics as needed.

• Lead teams through periods of rapid growth, transformation, and scaling with clarity and confidence.

Qualifications

• Education: Bachelor’s or Master’s in Life Sciences, Engineering, or Business is required; an MBA is often preferred

• Experience: 6-10 years of experience working in Biotech, Pharmaceutical Operations, or Medical Device companies, including leadership roles

• Skills: Strong knowledge of GMP/GxP compliance and regulatory landscapes is required.

Preferred Qualifications:

• Experience in Lean Manufacturing and Six Sigma

• Experience implementing ERP, MES, or Advanced Planning Solutions

• Experience with semiconductor manufacturing and packaging processes

• Experience with a product introduction that achieved 510K compliance

• Experience leading operations at a company that scaled to over $500M

Nautilus Team Culture

• We are determined to do whatever it takes to get our platform into the hands of researchers who will use it to upend the status quo in basic research and healthcare.

• We work on cross functional teams, wear many hats, take risks to work through uncertainty, enjoy working collaboratively on challenging problems, and celebrate one another’s victories.

• We go above and beyond, but also strive to provide a supportive atmosphere of colleagues who are willing to lend a helping hand and make working at Nautilus not only fulfilling in its end goals, but enjoyable on a day-to-day basis.

Compensation Range: $189K - $252K