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Manufacturing Technician

Nautilus Biotechnology

Nautilus Biotechnology

San Carlos, CA, USA
Posted on Mar 23, 2026

Location

San Carlos

Employment Type

Full time

Location Type

On-site

Department

Operations

Compensation

  • $71K – $104K • Offers Equity

The hiring pay range for this position is based on skills, education, and experience relevant to the role. New hires are typically hired into the low to midpoint of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. Pay ranges are adjusted based on cost of labor in each respective geographical market. Your recruiter can share more about the specific pay range for your location during the hiring process.

Benefits include medical, vision, and dental insurance, group and supplemental life insurance, 401k retirement plan, responsible paid time off, parental leave, and more. Other components of total compensation include a competitive options grant at the time of hire (with potential for additional grants).

At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.

We are hiring a Manufacturing Technician to join our growing team. This technician will support the assembly and build of our instrument platform. This role will focus on hands-on assembly of complex electromechanical systems including mechanical structures, fluidic systems, and internal electrical wiring within a complex instrument chassis. The Manufacturing Technician will play a critical role in executing prototype and pilot builds, supporting the transition from engineering development to scalable manufacturing. The ideal candidate is comfortable working in a fast-paced development environment and has experience assembling complex scientific or electromechanical instrumentation.

Responsibilities

  • Perform hands-on assembly of complex electromechanical instruments

  • Assemble mechanical chassis, structural components, and internal subassemblies

  • Install and route fluidic systems, including tubing, manifolds, pumps, and valves

  • Install and route electrical wiring and harnesses within instrument enclosures

  • Integrate mechanical, electrical, and fluidic subsystems within the instrument chassis

  • Execute engineering prototype builds, design verification builds, and pilot production builds

  • Follow detailed work instructions and assembly procedures

  • Verify correct installation and alignment of components during assembly

  • Escalate assembly issues or deviations to engineering or operations teams

  • Support troubleshooting and rework activities when required

  • Complete required manufacturing documentation including Device History Records (DHR), build travelers, traceability records

  • Record serial numbers and part traceability information

  • Document deviations or observations during builds

  • Provide redlines or suggested improvements to assembly instructions

  • Provide feedback to engineering and operations teams regarding build challenges or assembly issues

  • Document observations that may improve manufacturability or assembly efficiency

  • Support continuous improvement of assembly processes during pilot builds

Requirements

  • 3–7+ years of experience assembling complex electromechanical systems

  • Experience working with mechanical assemblies, fluidics, and electrical wiring

  • Experience working in prototype, NPI, or pilot manufacturing environments

  • Preferred industries include:

    • Biotechnology / life sciences instrumentation

    • Medical devices

    • Analytical instrumentation

    • Semiconductor equipment

    • Aerospace instrumentation

Additional Requirements

  • Strong attention to detail and assembly quality

  • Ability to work independently after initial training

  • Comfortable working in a fast-paced development environment

  • Ability to identify and escalate build issues quickly

  • Strong communication skills and ability to work cross-functionally with engineering teams

Compensation Range: $71K - $104K