Invest in your career with a Madrona-funded company.

Vilya is a computational biotechnology company creating a novel class of medicines to precisely target disease biology. We believe computational approaches are an integral, if not foundational, component of drug discovery and development.

We are harnessing the power of our platform to go after previously impossible targets in an array of indications. Vilya’s ultimate goal is to solve some of the most challenging unmet medical needs that exist today.

Our Vision: Harness a revolution in technology and biology to better human health.

Our Mission: Build an independent, leading biotech company founded on intelligent drug design to cure the incurable.

We are seeking a Senior Scientist, High Throughput Screening to support our macrocycle discovery efforts. You will join a Series A-stage biotech startup co-founded by Nobel Prize-winning scientist David Baker, where the pace and flexibility of an early-stage company create significant opportunities for impact. You will work closely with a talented team, build a broad range of skills, and help shape Vilya’s culture, strategic direction, and research outcomes.

Vilya is a team-first organization, and we believe onsite work is essential to how we collaborate, move quickly, and build a strong culture. This is a fully onsite position in our South San Francisco office. Join us and help make a difference for patients!

RESPONSIBILITIES:

• Independently design, develop, and execute biochemical, biophysical and cell based assays ensuring assay robustness and reproducibility
• Minaturize and optimize assays for screening and SAR.
• Lead high-throughput screening (HTS) campaigns for various drug targets, including automated workflows, to drive preclinical drug discovery
• Collaborate frequently and effectively across biology, chemistry, automation, informatics, compute, and compound management teams to ensure seamless handoff of information and materials
• Analyze and QC experimental results, draw conclusions, and recommend future experiments
• Prepare written reports and presentations summarizing experimental outcomes and project status for peers and leadership
• Clearly communicate data, plans, and progress to the broader Vilya team
• Provide scientific expertise and make recommendations for new assays, screening technologies, instrumentation and improved screening workflows
• Proactively review scientific literature to incorporate new discoveries and technologies into Vilya’s research efforts
• Organize and maintain electronic work records
• Participate in project teams as biology representative and subject matter expert
• Demonstrate adaptability and flexibility in evolving environments and the ability to execute with urgency

PREFERRED QUALIFICATIONS:

• Ph.D. or equivalent industry experience in Cell Biology, Molecular Biology, or Biochemistry
• Demonstrated leadership experience in an industry role (e.g., project team lead, people management, or program management)
• Experience with drug discovery laboratory techniques
• Hands on industry experience with automation and HTS using a variety of assay technologies
• Familiarity with automated liquid handling (e.g. Biomek i7, Formulatrix Tempest)
• Strong problem solving skills and ability to work collaboratively in a fast paced, team-first environment
• Passion for scientific discovery and making a difference in the world

VILYA BENEFITS:

• Opportunity to work in a disruptive startup with a talented, experienced, and dedicated team
• 401(k) plan with employer matching for contributions
• Stock options
• Excellent medical, dental, and vision coverage
• Open, flexible vacation policy
• Support to attend professional conferences meaningful to your career growth
• Monthly cell phone and internet stipend
• Monthly wellness and commuter stipend

Salary Range: $125,000–$164,000/year